• Achieving hidradenitis suppurativa response score is associated with significant improvement in clinical and patient-reported outcomes: Post hoc analysis of pooled data from PIONEER I and II 

      Kimball, Alexandra Boer; Tzellos, Thrasyvoulos; Calimlim, Brian M; Teixeira, Henrique D; Geng, Ziqian; Okun, Martin M (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-08-07)
      Hidradenitis Suppurativa Clinical Response (HiSCR), is a validated tool that has been used to assess the efficacy of adalimumab among patients with hidradenitis suppurativa. We evaluated the clinical meaning of HiSCR by relating it to patient-reported outcomes to give further context to its achievement in a post hoc analysis of integrated data from two phase 3 clinical trials (PIONEER I and II). ...
    • Hidradenitis suppurativa/acne inversa: a practical framework for treatment optimization - systematic review and recommendations from the HS ALLIANCE working group 

      Zouboulis, Christos C.; Bechara, Falk Georges; Dickinson-Blok, Janine L.; Gulliver, Wayne Peter Frances; Horváth, Barbara H.; Hughes, Rosalind; Kimball, Alexandra Boer; Kirby, Brian; Martorell, Antonio; Podda, Maurizio; Prens, Errol Prospero; Ring, Hans Christian; Tzellos, Thrasyvoulos; van der Zee, Hessel H.; van Straalen, Kelsey R.; Vossen, Allard R.J.V.; Jemec, Gregor Borut Ernst (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-09-03)
      Hidradenitis suppurativa (HS)/acne inversa is a debilitating chronic disease that remains poorly understood and difficult to manage. Clinical practice is variable, and there is a need for international, evidence‐based and easily applicable consensus on HS management. We report here the findings of a systematic literature review, which were subsequently used as a basis for the development of international ...